--- a/browser/components/preferences/in-content/advanced.js
+++ b/browser/components/preferences/in-content/advanced.js
@@ -74,16 +74,25 @@ var gAdvancedPane = {
                      gAdvancedPane.updateWritePrefs);
     setEventListener("showUpdateHistory", "command",
                      gAdvancedPane.showUpdates);
 #endif
     setEventListener("viewCertificatesButton", "command",
                      gAdvancedPane.showCertificates);
     setEventListener("viewSecurityDevicesButton", "command",
                      gAdvancedPane.showSecurityDevices);
+
+#ifdef MOZ_WIDGET_GTK
+    // GTK tabbox' allow the scroll wheel to change the selected tab,
+    // but we don't want this behavior for the in-content preferences.
+    let tabsElement = document.getElementById("tabsElement");
+    tabsElement.addEventListener("DOMMouseScroll", event => {
+      event.stopPropagation();
+    }, true);
+#endif
   },
 
   /**
    * Stores the identity of the current tab in preferences so that the selected
    * tab can be persisted between openings of the preferences window.
    */
   tabSelectionChanged: function ()
   {