--- a/dom/media/platforms/agnostic/VPXDecoder.cpp
+++ b/dom/media/platforms/agnostic/VPXDecoder.cpp
@@ -118,21 +118,16 @@ VPXDecoder::Flush()
   });
 }
 
 RefPtr<MediaDataDecoder::DecodePromise>
 VPXDecoder::ProcessDecode(MediaRawData* aSample)
 {
   MOZ_ASSERT(mTaskQueue->IsCurrentThreadIn());
 
-#if defined(DEBUG)
-  NS_ASSERTION(IsKeyframe(*aSample, mCodec) == aSample->mKeyframe,
-               "VPX Decode Keyframe error sample->mKeyframe and sample data out of sync");
-#endif
-
   if (vpx_codec_err_t r = vpx_codec_decode(&mVPX, aSample->Data(), aSample->Size(), nullptr, 0)) {
     LOG("VPX Decode error: %s", vpx_codec_err_to_string(r));
     return DecodePromise::CreateAndReject(
       MediaResult(NS_ERROR_DOM_MEDIA_DECODE_ERR,
                   RESULT_DETAIL("VPX error: %s", vpx_codec_err_to_string(r))),
       __func__);
   }