--- a/layout/base/nsPresShell.cpp
+++ b/layout/base/nsPresShell.cpp
@@ -7363,16 +7363,22 @@ PresShell::HandleEvent(nsIFrame* aFrame,
                  "How did we end up outside the connected prescontext/viewmanager hierarchy?");
     // If we aren't starting our event dispatch from the root frame of the root prescontext,
     // then someone must be capturing the mouse. In that case we don't want to search the popup
     // list.
     if (framePresContext == rootPresContext &&
         frame == mFrameConstructor->GetRootFrame()) {
       nsIFrame* popupFrame =
         nsLayoutUtils::GetPopupFrameForEventCoordinates(rootPresContext, aEvent);
+      // If a remote browser is currently capturing input break out if we
+      // detect a chrome generated popup.
+      if (popupFrame && capturingContent &&
+          EventStateManager::IsRemoteTarget(capturingContent)) {
+        capturingContent = nullptr;
+      }
       // If the popupFrame is an ancestor of the 'frame', the frame should
       // handle the event, otherwise, the popup should handle it.
       if (popupFrame &&
           !nsContentUtils::ContentIsCrossDocDescendantOf(
              framePresContext->GetPresShell()->GetDocument(),
              popupFrame->GetContent())) {
         frame = popupFrame;
       }