--- a/toolkit/xre/nsAppRunner.cpp
+++ b/toolkit/xre/nsAppRunner.cpp
@@ -5156,19 +5156,23 @@ bool BrowserTabsRemoteAutostart() {
     } else {
       status = kE10sDisabledByUser;
     }
   } else {
     gBrowserTabsRemoteAutostart = true;
   }
 
   // Uber override pref for emergency blocking
-  if (gBrowserTabsRemoteAutostart && EnvHasValue("MOZ_FORCE_DISABLE_E10S")) {
-    gBrowserTabsRemoteAutostart = false;
-    status = kE10sForceDisabled;
+  if (gBrowserTabsRemoteAutostart) {
+    const char* forceDisable = PR_GetEnv("MOZ_FORCE_DISABLE_E10S");
+    // The environment variable must match the application version to apply.
+    if (forceDisable && !strcmp(forceDisable, gAppData->version)) {
+      gBrowserTabsRemoteAutostart = false;
+      status = kE10sForceDisabled;
+    }
   }
 
   gBrowserTabsRemoteStatus = status;
 
   return gBrowserTabsRemoteAutostart;
 }
 
 bool FissionAutostart() {