--- a/js/xpconnect/src/XPCWrappedJSClass.cpp
+++ b/js/xpconnect/src/XPCWrappedJSClass.cpp
@@ -503,18 +503,23 @@ nsXPCWrappedJSClass::DelegatedQueryInter
     // We can't have a cached wrapper.
     if (aIID.Equals(NS_GET_IID(nsWrapperCache))) {
         *aInstancePtr = nullptr;
         return NS_NOINTERFACE;
     }
 
     // QI on an XPCWrappedJS can run script, so we need an AutoEntryScript.
     // This is inherently Gecko-specific.
+    // We check both nativeGlobal and nativeGlobal->GetGlobalJSObject() even
+    // though we have derived nativeGlobal from the JS global, because we know
+    // there are cases where this can happen. See bug 1094953.
     nsIGlobalObject* nativeGlobal =
       NativeGlobal(js::GetGlobalForObjectCrossCompartment(self->GetJSObject()));
+    NS_ENSURE_TRUE(nativeGlobal, NS_ERROR_FAILURE);
+    NS_ENSURE_TRUE(nativeGlobal->GetGlobalJSObject(), NS_ERROR_FAILURE);
     AutoEntryScript aes(nativeGlobal, /* aIsMainThread = */ true);
     XPCCallContext ccx(NATIVE_CALLER, aes.cx());
     if (!ccx.IsValid()) {
         *aInstancePtr = nullptr;
         return NS_NOINTERFACE;
     }
 
     // We support nsISupportsWeakReference iff the root wrapped JSObject